Leon Y. Deouell

Main research areas

  • Conscious awareness, its neural basis, and its breakdown in stroke patients
  • The neural representation of acoustic space
  • Visual representation across time and space (eye movements)
  • Temporal and non-temporal predictions
  • Methodology of human electrophysiology (EEG and ECOG)

Vita

Ausbildung

1985-1988

B.M.Sc. (Summa Cum Laude), Sackler School of Medicine, Tel Aviv University

1988-1993

M.D. (Summa Cum Laude), Sackler School of Medicine,Tel Aviv University

1992-1993

Internship (medicine) at the Beilinson Hospital, Petach Tikva, Israel

1999-2000

Resident, Physical Medicine and Rehabilitation, Loewenstein Rehabilitation Center, Raanana, Israel (not completed)

1993-2001

Ph.D (With distinction), Department of Psychology, The Hebrew University of Jerusalem. Supervisor: Prof. Shlomo Bentin

2000-2003

Post-doctoral fellowship at the Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley. Advisors: Prof. Robert T. Knight, Prof. Mark D’Esposito

Werdegang

1994-1996

Teaching assistant, School of Education, Hebrew University

1999-2000

Ad-hoc lecturer, Department of Psychology, Hebrew University

2003 -2008

Senior lecturer, Department of Psychology, Hebrew University

2008- 2009

Associate Professor, Department of Psychology, Hebrew University

2009 –

Full professor, Department of Psychology and Edmond and Lily Safra Center for Brain Sciences, Hebrew University

2006  - 2012

2015 - 2017

Chair, Cognitive neuroscience and Neuropsychology graduate program at the department of Psychology, Hebrew University

2012 - 2015

Chair, Department of Psychology, Hebrew University

2012-

Academic director, Neuroimaging Unit, Edmond and Lily Safra Center for Brain Sciences, Hebrew University

2010 - 2011

Visiting Scholar, Helen Wills Neuroscience Institute, University of California, Berkeley

 

Co-founder and CSO, InnerEye, Israel

Advisory board, Elminda, Israel

 

 

Publications

PhD Dissertation (2001)

Title: Preattentive Spatial Encoding and Awareness: Evidence from Mismatch Negativity Studies in Unilateral Neglect. 

Supervisor: Prof. Shlomo Bentin

 

Chapters in Collections (edited books)

Furstenberg, A., Deouell, L.Y., Sompolinsky, H. (in 2014). Change of Intention in ‘Picking’ Situations. In: Surrounding Free Will, A. Mele (Ed.), Oxford University Press.

Mudrik, L. Deouell, L.Y., Lamy, D. (2013) Novelty, not integration: finding the function of conscious awareness. In: Kreitler, S. and Maimon, O. (Eds.) Consciousness: Its nature and functions. Hauppage, NY: Nova Publishers. 

Deouell, L.Y., Ivry, R.B., & Knight, R.T. (2002) Electrophysiological methods and transcranial magnetic stimulation in behavioral neurology and neuropsychology. In: Feinberg, T.E. and Farah, M.J. (Eds.) Behavioral Neurology and Neuropsychology. Second Edition. NY: McGraw-Hill.

Deouell, L.Y., & Knight, R.T. (2005). Lateral Prefrontal Damage Affects Multiple Elements Of Selective Attention - Electrophysiological Evidence. In: Itty, L., Rees G. & Tsotos, J. (Eds.) Neurobiology of Attention. Elsevier. 

Deouell, L.Y. & Knight, R.T. (2008). Executive Functions: EEG Studies in Neurological patients. In L. Squire (ed.), The new encyclopedia of neuroscience. Amsterdam: Elsevier. 

 

Articles

Marciano-Romm D., Bentin, S. Deouell, L.Y. (2018). Alternative outcomes create biased expectations regarding the received outcome: evidence from event-related potentials. Neuropsychologia, 13, 126-139.

Breska, A., Deouell, L.Y. (2017). Dance to the rhythm, cautiously: isolating unique indicators of oscillatory entrainment. PLOS Biology, 15(9), e2003534.

Golan, T., Davidesco, I., Meshulam, M., Groppe, D. M., Megevand, P., Yeagle, E. M., Goldfinger, M. S., Harel, M., Melloni, L., Schroeder, C. E., Deouell, L. Y., Mehta, A. D., Malach, R. (2017). Increasing suppression of saccade-related transients along the human visual hierarchy. eLife, 6.

Shrem, T., Murray, MM, Deouell, L.Y. (2017). Auditory-visual integration modulates location-specific repetition suppression of auditory responses. Psychophysiology, 54, 1663-1675.

Gerber, E. M.,Golan,T., Knight, R. T., Deouell, L. Y. (2017). Persistent neural activity encoding real-time presence of visual stimuli decays along the ventral stream. Neuroimage, 161, 67-79.

Breska, A., Deouell, L.Y. (2017), Neural Mechanisms of Rhythm-based Temporal Prediction: Delta Phase-locking Reflects Temporal Predictability but not Rhythmic Entrainment. PLOS Biology. 15(2): e2001665

Shrem, T., Deouell, L.Y. (2017). Hierarchies of Attention and Experimental Designs: Effects of Spatial and Intermodal Attention Revisited. Journal of Cognitive Neuroscience, 29(1), 203-219.

Gerber, E. M., Sadeh, B., Ward, A., Knight, R. T., & Deouell, L. Y. (2016). Non-Sinusoidal Activity Can Produce Cross-Frequency Coupling in Cortical Signals in the Absence of Functional Interaction between Neural Sources. Plos One, 11(12), e0167351.

Golan, T., Davidesco, I., Meshulam, M., Groppe, D. M., Mégevand, P., Yeagle, E. M., Goldfinger, M. S., Harel, M., Melloni, L., Schroeder, C. E.  Deouell, L. Y., Mehta, A. D., Malach, R. (2016). Human Intracranial recordings link suppressed transients rather than 'filling-in' to perceptual continuity across blinks. eLife, 5, e17243.

Breska, A., Deouell, L.Y. (2016). When synchronizing to rhythms is not a good thing: Modulations of preparatory and post-target neural activity when shifting attention away from on-beat times of a distracting rhythm. Journal of Neuroscience, 36(27), 7154-7166.

Harel, A., Groen, II, Kravitz, D. J., Deouell, L. Y., & Baker, C. I. (2016). The Temporal Dynamics of Scene Processing: A Multifaceted EEG Investigation. eNeuro, 3(5).

Dürschmid S., Edwards E., Reichert, C., Dewar, C., Hinrichs, H., Heinze H-J., Kirsch, H.E., Dalal, S.S., Deouell, L.Y., Knight, R.T. (2016) Hierarchy of prediction errors for auditory events in human temporal and frontal cortex. Proceedings of the National Academy of Science, 113, 6755-60.

Deouell L.Y, Grill-Spector K., Malach R., Murray M.M., Rossion B. (2016). Introduction to the special issue on functional selectivity in perceptual and cognitive systems - a tribute to Shlomo Bentin (1946-2012). Neuropsychologia, 83, 1-4. 

Pfeiffer, T., Heinze, N., Frysch, R., Deouell, L.Y., Schoenfeld, M.A., Knight, R.T., and Rose, G. (2016). Extracting duration information in a picture category decoding task using hidden Markov Models. J Neural Eng 13, 026010.

Deouell, L.Y (2016). Microsaccades mediate a bottom-up mechanism for cross frequency coupling in early visual cortex. (Commentary on Lowet et al.) European Journal of Neuroscience, 43, 1284-5.

Marciano-Romm D., Romm A., Bourgeois-Gironde S., Deouell L.Y. (2016). The Alternative Omen Effect: Illusory negative correlation between the outcomes of choice options.Cognition,.146, 324-338.

Furstenberg, A., Breska, A., Sompolinsky, H., & Deouell, L. Y. (2015). Evidence of Change of Intention in Picking Situations. Journal of Cognitive Neuroscience. 27, 2133-46

Mudrik, L., Shalgi, S., Lamy, D., and Deouell, L.Y. (2014). Synchronous contextual irregularities affect early scene processing: Replication and extension. Neuropsychologia 56, 447-458.

Shrem, T., and Deouell, L.Y. (2014). Frequency-dependent auditory space representation in the human planum temporale. Frontiers in Human Neuroscience 8.

Breska, A, Deouell, L.Y. (2014). Automatic bias of temporal expectations following temporally regular input independently of high-level temporal expectation. Journal of Cognitive Neuroscience, 26, 1555-71.

Fuhrmann-Alpert, G., Manor, R., Shpanier, A., Deouell, L.Y., Geva, A. (2014) Spatio-Temporal Representations of Rapid Visual Target Detection: A Single Trial EEG Classification Algorithm. IEEE Transactions on Biomedical Engineering (TBME), 61, 2290-303.

Bonato, M., Deouell, L. Y. (2013). Hemispatial neglect: Computer-based testing allows more sensitive quantification of attentional disorders and recovery and might lead to better evaluation of rehabilitation. Frontiers in Human Neuroscience 7. doi: 10.3389/fnhum.2013.00162

Shalgi, S. and Deouell, L. Y. (2013). "Is there any electrophysiological evidence for subliminal error processing?" Frontiers in neuroscience 7: 150.

Oren, N., Soroker, N. and Deouell, L.Y. (2013). "Immediate effects of exposure to positive and negative emotional stimuli on visual search characteristics in patients with unilateral neglect." Neuropsychologia 51(13): 2729-2739.

Shalgi, S., Deouell, L.Y. (2012). Is any awareness necessary for an Ne? Frontiers in Human Neuroscience, 6:124.

Schechtman, E., Shrem, T., Deouell, L.Y. (2012). Spatial Localization of Auditory Stimuli in Human Auditory Cortex is Based on Both Head-independent and Head-centered Coordinate Systems. Journal of Neuroscience, 32, 13501-13509.

Ramot, M., Wilf, M., Goldberg, H., Weiss, T., Deouell, L. Y., & Malach, R. (2011). Coupling between spontaneous (resting state) fMRI fluctuations and human oculo-motor activity. Neuroimage, 58(1), 213-225.

Mudrik, L., Breska, A., Lamy, D. & Deouell, L.Y. (2011). Integration without awareness: expanding the limits of unconscious processing. Psychological Science, 22, 764-70.

Mudrik L, Deouell L.Y.  & Lamy D. (2011) Scene congruency biases Binocular Rivalry.Consciousness and Cognition. 20, 756-767.

Amihai, I., Deouell, L.Y., & Bentin, S. (2011). Neural adaptation is related to face repetition irrespective of identity: a reappraisal of the N170 effect. Experimental Brain Research, 209, 193-204.

Amihai, I., Deouell, L.Y., & Bentin, S. (2011) Conscious awareness is necessary for processing race and gender information from faces. Consciousness and Cognition, 20, 269-279

Haroush K, Deouell L.Y.  & Hochstein S, & (2011). Hearing While Blinking: Multisensory Attentional Blink Revisited. Journal of Neuroscience, 31, 922-927.

Yuval-Greenberg, S. & Deouell, L.Y. (2011). Scalp-Recorded Induced Gamma-Band Responses to Auditory Stimulation and Its Correlations with Saccadic Muscle-Activity. Brain Topography, 24:30–39.

Bendixen, A., Grimm, S., Deouell, L.Y., Wetzel, N., Mädebach, A. & Schröger, E. (2010). The time-course of auditory and visual distraction effects in a new crossmodal paradigm. Neuropsychologia 48, 2130-2139.

Keren, A. S., Yuval-Greenberg, S., & Deouell, L.Y. (2010) Saccadic Spike Potentials in Gamma-Band EEG:  Characterization, Detection and Suppression. Neuroimage, 49, 2248-2263.

Mudrik, L., Lamy, D., Deouell, L.Y. (2010). ERP evidence for context congruity effects during simultaneous object-scene processing. Neuropsychologia, 48, 507-517.

Haroush K, Hochstein S, & Deouell L.Y. (2010). Momentary Fluctuations in Allocation of Attention: Cross-modal Effects of Visual Task Load on Auditory Discrimination. Journal of Cognitive Neuroscience, 22, 1440-1451. 

Yuval-Greenberg, S., Keren, A. S., Tomer, O., Nelken, I., & Deouell, L.Y. (2009). Response to Letter: Melloni et al., "Transient Induced Gamma-Band Response in EEG as a Manifestation of Miniature Saccades." Neuron 58, 429-441. Neuron, 62, 10-12.

Yuval-Greenberg, S., & Deouell, L.Y. (2009). The Broadband-Transient Induced Gamma-Band Response in Scalp EEG Reflects the Execution of Saccades. Brain Topography, 22, 3-6.

Cicek M., Deouell L.Y., Knight R.T. (2009). Brain Activity During Landmark And Line Bisection Tasks. Frontiers in Human Neuroscience, 3:7.

Kaufman, A., Serfaty, C., Deouell, L.Y., Ruppin, E., and Soroker, N. (2009). Multi perturbation analysis of distributed neural networks: the case of spatial neglect. Human Brain Mapping, 30, 3687-95.

Shalgi, S., Barkan, I., Deouell, L.Y. (2009) On the Positive Side of Error Processing: Error Awareness Positivity Revisited. European Journal of Neuroscience, 29, 1522-1532.

Grimme, S. Bendixen, A., Deouell, L.Y., Schröger, E. (2009) Distraction in a visual multi-deviant paradigm: Behavioral and event-related potential effects. International Journal of Psychophysiology, 72, 260-266.

Yuval-Greenberg, S. & Deouell, L.Y. (2009). The Dog's Meow: Asymmetrical Interaction in Cross-Modal Object Recognition. Experimental Brain Research, 193, 603-14.

Yuval-Greenberg, S., Tomer, O., Keren, O.S., Nelken, I., Deouell, L.Y. (2008). Transient induced gamma-band response in EEG as a manifestation of miniature saccades. Neuron, 58, 429-441.

Moberget, T., Karns, C.M., Deouell, L.Y., Lindgren, M., Knight, R.T., Ivry, M. (2008). Detecting violations of sensory expectancies following cerebellar damage: a mismatch negativity study. Neuropsychologia, 46, 2569-2579. 

Miller, B.T., Deouell, L.Y., Dam, C., Knight, R.T., D’Esposito, M. (2008) Spatio-Temporal Dynamics of Neural Mechanisms Underlying Component Operations in Working Memory. Brain Research, 1206, 61-75.

Grimm, S., Schröger, E., Bendixen, A., Bäß, P., Roye,  A., Deouell, L.Y. (2008) Optimizing the auditory distraction paradigm: Behavioral and event-related potential effects in a lateralized multi-deviant approach. Clinical Neurophysiology, 119, 934-947.

Lamy, D. Mudrik, L., Deouell, L.Y. (2008) Unconscious auditory information can prime visual word processing: A process-dissociation procedure study. Consciousness and Cognition, 17, 688-698.

Deouell, L.Y., Deutsch, D., Scabini, D., Knight, R.T. (2008) No disillusions in Auditory Extinction: Perceiving a Melody Comprised of Unperceived Notes. Frontiers in Human Neuroscience, 1:15. doi:10.3389/neuro.09/015.2007

Deouell, L.Y. (2007). The frontal generator of the mismatch negativity revisited. Journal of Psychophysiology, 21,188–203.

Deouell, L.Y., Heller, A.S., Malach , R., D’Esposito , M., Knight, R.T . (2007). Cerebral Responses to Change in Spatial Location of Unattended Sounds. Neuron 55, 985-996.

Shalgi, S. O’Connell, R.G., Deouell, L.Y., & Robertson , I.H. (2007). Absent Minded but Accurate: Delaying responses increases Accuracy but decreases Error Awareness. Experimental Brain Research. 182, 119-24. 

Zion-Golumbic, E, Deouell, L.Y., Whalen, D.H., & Bentin, S. (2007). Representation of harmonic frequencies in auditory memory: a mismatch negativity study. Psychophysiology, 44, 671-9

Yuval-Greenberg, S. & Deouell, L.Y. (2007) What you see is not (always) what you hear: Induced gamma band responses reflect cross-modal interactions in familiar object recognition. Journal of Neuroscience 31;27(5):1090-6. 

Shalgi, S. & Deouell, L.Y. (2007). Direct Evidence for Differential Roles of Temporal and Frontal Components of Auditory Change Detection. Neuropsychologia, 45(8):1878-88.

Deouell, L. Y., Parnes, A., Pickard, N., & Knight, R. T. (2006). Spatial location is accurately tracked by human auditory sensory memory: evidence from the mismatch negativity. European Journal of Neuroscience, 24, 1488-1494. 

Edwards E., Soltani, M., Deouell, L.Y., Berger, M.S. & Knight, R.T. (2005) High gamma activity in response to deviant auditory stimuli recorded directly from human cortex. Journal of Neurophysiology, 94, 4269-4280.

Deouell, L.Y., Sacher, Y. & Soroker, N. (2005) Assessment of spatial attention after brain damage with a dynamic reaction time test. Journal of The International Neuropsychological Society, 11, 697-707. 

Sacher Y, Serfaty C., Deouell L.Y., Sapir A., Henik A., & Soroker N(2004). Role of disengagement failure and attentional gradient in unilateral spatial neglect – a longitudinal study. Disability and Rehabilitation, 26, 746-55.

D'Esposito, M. , Deouell, L.Y., & Gazzaley, A. (2003). Alterations in the BOLD fMRI signal with ageing and disease: a challenge for neuroimaging. Nature Reviews Neuroscience, 4, 863-872. 

Hasson, U., Avidan, G., Deouell, L.Y., Bentin, S., & Malach, R.   (2003). Face-selective activation in a congenital prosopagnosic subject. Journal of Cognitive Neuroscience, 15, 419-31. 

Deouell, L.Y., Karns, C.M., Harrison, T.B., & Knight, R.T. (2003). Spatial asymmetries of auditory event-synthesis in humans. Neuroscience Letters, 335, 171-4. 

Deouell, L.Y. (2002). Pre-requisites for conscious awareness: Clues from electrophysiological and behavioral studies of unilateral neglect patients. Consciousness and Cognition, 11, 546-567. 

Raz, A., Deouell, L.Y. and Bentin, S. (2001). Is Pre-Attentive Processing Compromised by Prolonged Wakefulness? Effects of Total Sleep Deprivation on the Mismatch Negativity. Psychophysiology, 38, 787-795. 

Deouell, L.Y., Bentin, S. & Soroker, N. (2000). Electrophysiological evidence for an early (pre-attentive) information processing deficit in patients with right hemisphere damage and unilateral neglect. Brain, 123, 353-365.  

Deouell, L.Y., Soroker, N.(2000) What is extinguished in auditory extinction? Neuroreport, 11:3059-62. 

Deouell L.Y., Hämäläinen, H. & Bentin, S. (2000). Unilateral Neglect Following Right Hemisphere Damage: Contributions From Event Related Potentials. Audiology and Neuro-Otology, 5:225-34. 

Bentin, S. & Deouell, L.Y. (2000). Face detection and face identification: ERP evidence for separate mechanisms. Cognitive Neuropsychology, 17:35-55. 

Bentin, S., Deouell, L.Y. & Soroker, N. (1999). Selective streaming of visual information in face recognition: Evidence from developmental prosopagnosia. Neuroreport 10, 823-827. 

Deouell, L.Y. , & Bentin, S. (1998). Variable cerebral responses to equally distinct deviance in four auditory dimensions: A mismatch negativity study. Psychophysiology, 35, 745-754. 

Deouell, L.Y. , Bentin, S., & Giard, M. H. (1998). Mismatch negativity in dichotic listening: evidence for interhemispheric differences and multiple generators. Psychophysiology, 35(4), 355-365. 

Awards & Grants

Awards & Grants

2017-2018 

Israel Ministry of Science and Technology, China-israel cooperative scientific research,  Cognitive and Neural Underpinnings of Retaining Bindings in Working Memory, 507,000 NIS

2014-2018 

Israel Science Foundation, Investigating visual object processing with and without awareness using human electrophysiology in free viewing. $240,000

2014-2018 

US-Israel Binational Science Foundation, Object persistence over time - behavioral, electrocorticogrpahic and electroencephalographic study in humans, (with Prof. Robert T. Knight, UC Berkeley) $200,000

2013-2015 

HU – EPFL collaboration program, Get (re)Connected: Recovery from Stroke, A New Approach Linking Neuroanatomy,  Neurophysiology and Behavior (with Dr. Dimitry van de Ville, EPFL), €80,000

2011-2013 

Templeton Foundation, Volition, Intention and Priming: elucidating the interface using behavioral and EEG experimentation, neural network modeling and philosophical analysis, $261,000

2009 – 2011 

MAFAT, Ministry of Security, Israel,  “Characterization of single trials during image viewing”, $370,000

2008-2010 

National Institute of Psychobiology extended grant, “In the eyes of the beholder: The correlation between induced gamma band responses and eye movements, $100,000

2008-2012 

Israel Science Foundation (ISF), “Systematic characterization of a neural system for spatial localization of background sounds in humans” ~$160,000

2005-2008

Israel Science Foundation (ISF), “Pre-attentive auditory-visual interactions in space - A neurophysiological and neuropsychological investigation”, $153,000

2006-2009

German-Israeli Foundation (GIF), “The neuroscience of distraction and involuntary attention”, Together with Erich Schröger (Leipzig), €75,000/150,000 

2004-2006

The National Institute of Psychobiology in Israel, “Electrophysiological investigation of interactions between background auditory change detection and auditory and visual processing at the focus of attention”, $50,000 

2006-2007

The National Institute of Psychobiology, “Is the frontal lobe involved in non-intentional change detection?”, $25,000